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J Neurophysiol

Severe gastrointestinal conditions Conditions like gastroparesis (delayed stomach emptying) may be worsened by GLP-1 medications, which slow gastric motility further

Exendin-4 increases bone mineral density in type 2 diabetic OLETF rats potentially through the down-regulation of SOST/sclerostin in osteocytes

While the initial approvals were for type 2 diabetes and chronic weight management, the data emerging from both clinical studies and real-world observation is compelling enough that many endocrinologists and reproductive specialists are already incorporating it into their treatment approaches for women with polycystic ovary syndrome

Inulin and fructooligosaccharides (FOS): These are prebiotic fibers found in foods like chicory root, garlic, onions, and Jerusalem artichokes